A to Z of MS
Click on the relevant link for more information on a topic.
A to Z of MS Vardenafil (Levitra)
Product name
Levitra
Vardenafil is a prescription medicine for the treatment of erectile dysfunction in men.
How vardenafil works
Erectile dysfuntion is the inability to achieve or maintain an erection sufficient for satisfactory sexual performance. In multiple sclerosis this is commonly associated with bladder problems and both disorders are believed to be as a direct result of damage to the nerves in the spinal cord.
Vardenafil works by delaying the action of enzymes called PDE5 (phosphodiesterase type 5), which regulate blood flow in the penis. Altering levels of this enzyme means that normal sexual stimulation leads to better erections.
How vardenafil is given
Vardenafil is taken orally about an hour before sexual activity is planned. Dose ranges from 5-20mg as necessary; maximum dose frequency is once a day. A soluble version was launched in 2011.
Side effects and contraindications
Common side effects include headaches, flushing, upset stomach, visual disorders, nasal congestion and dizziness. Vardenafil should not be taken by people receiving treatment with drugs containing nitrates, such as are used to treat angina. Vardenafil must be used with caution by people with existing heart conditions or problems with liver or kidney function or low blood pressure.
Patient Information Leaflet
- Levitra (EMC website)