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A to Z of MSAlprostadil

Product name

Caverject, MUSE, Viridal Duo

Alprostadil is a vasodilator for the treatment of erectile dysfunction. The NICE Guideline states that treatment with alprostadil may be considered where general and specific factors that cause or worsen erectile dysfunction have been assessed and there has been no response to sildenafil (Viagra).

How alprostadil works

Alprostadil works by causing blood vessels to expand, increasing blood flow. When this is administered to the penis the increased blood flow results in an erection.

How alprostadil is given

Alprostadil in the form of MUSE is administered by application into the opening at the end of the penis (urethra). Alprostadil is also available as an injection for injection directly into the penis (Caverject or Viridal Duo) or as a gel.

Side effects and contraindications

Common side effects can include prolonged erection lasting more than one hour, headache and dizziness and pain in the penis or urethra.

Reference

Landtblom AM.
Treatment of erectile dysfunction in multiple sclerosis.
Expert Review Of Neurotherapeutics 2006;6(6):931-935.
abstract

Sexual issues for men with MS
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